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Pharmacokinetics: Barbiturates are absorbed in various levels subsequent oral, rectal, or parenteral administration. The salts tend to be more promptly absorbed than are the acids. The onset of action for oral or rectal administration differs from 20 to 60 minutes. For IM administration, the onset of action is somewhat more rapidly. Pursuing IV adm

phenobarbital will reduce the extent or influence of diazepam buccal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. Solid or average CYP3A4 inducers might improve price of diazepam elimination; hence, efficacy of diazepam may be decreased.Most reviews of clinically significant drug interactions happening Toget